Calcitonin, amylin, CGRP and adrenomedullin

. 2009 Nov;158(Suppl 1):S30–S31. doi: 10.1111/j.1476-5381.2009.00501_16.x

Nomenclature	Calcitonin (CT)	AMY₁	AMY₂	AMY₃
Composition	CALCR	CALCR+RAMP1	CALCR+RAMP2	CALCR+RAMP3
Principal transduction	G_s/G_q	G_s	G_s	G_s
Rank order of potency	Salmon CT ≥ human CT ≥ AMY, CGRP > AM, AM2/IMD	AMY_1(a): Salmon CT ≥ AMY ≥ CGRP > AM2/IMD > human CT > AM	Poorly defined	AMY_3(a): Salmon CT ≥ AMY > CGRP > AM2/IMD > human CT > AM
Selective agonists	Human CT	AMY	AMY	AMY
Probes	[¹²⁵I]-CT (salmon, 0.1 nM), [¹²⁵I]-CT (human, 0.1–1.0 nM)	[¹²⁵I]-BH-AMY (rat, 0.1–1.0 nM)	[¹²⁵I]-BH-AMY (rat, 0.1–1.0 nM)	[¹²⁵I]-BH-AMY (rat, 0.1–1.0 nM)