. 2007 Feb;21(1):24–31. doi: 10.1055/s-2007-967744

Table 1.

Medications Known to Cause Eyelid Edema

Acetaminophen^*

Acetylcholinesterase inhibitors^*,^†

Acylovir^*

Albuterol^*

Aldosterone^*

Alprazolam^*

Amiodarone^*

Ampicillin^*

Amide and ester anesthetics^‡

Aproclonidine^‡

Aspirin^*,^†

Atropine^‡

Bacitracin^*

Bleomycin^*

Brimonidine^‡

Busulfan^*

Butabarbital^*

Carbamazepine^*

Carbimazole^*

Cephalosporins^*

Contact lens solutions (especially those containing the preservative benzalkonium chloride)^‡

Dexamethasone^*

Digitalis^*

Dorzolamide^‡

Erythromycin^*

Estrogens^†

Fluoroquinolones^*

Hydrocortisone^*

Ibuprofen^*,^†

Indomethacin^*,^†

Insulin^*

Iodine^‡

Penicillin^‡,^*

Phenylbutazone^*,^†

Pilocarpine^‡

Prednisone^*

Progesterone^†

Quinidine,^* quinine^*

Ranitidine (and other H₂ receptor blockers)^*

Rifampin^*

Sulindac^*,^†

Sympatholytics^*,^†

Temazepam^*

Tetracyclines^*

Thiabendazole^*

Triamcinolone^*

Triazolam^*

Vaccinations (including diphtheria, tetanus, pertussis vaccine, measles, mumps, rubella vaccine, poliovirus vaccine, rubella vaccine, rabies vaccine, rabies immune globulin, tetanus toxoid, and tetanus immune globulin),^* vancomycin^*

Vasodilators^*,^†

Verapamil^*

Known to cause urticaria/angioedema with eyelid swelling.

^†

Known to cause eyelid swelling due to generalized fluid retention.

^‡

Known to cause allergic contact blepharoconjunctivitis with eyelid swelling.