Fig. 5.

A549 and A549/BVDV-Npro cells were or were not pretreated with IFN for 18 h prior to infection with W3A at an m.o.i. of 0.01 p.f.u. per cell. At 4 days p.i., the cells were fixed and co-immunostained for STAT1 and PIV5 NP. Cells were visualized using a Zeiss LSM 5 Exciter confocal microscope. Arrows highlight cells at the edge of the plaque in which small viral cytoplasmic bodies can be detected and in which STAT1 has been degraded. A large, high-resolution copy of this image is available in JGV Online.