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(a) Virus titres in the supernatant and (b) viability of replicate cultures of NIH-3T3 cells pre-treated with control siRNA (empty bars) or PKR siRNA (filled bars) and infected (24 h later) with SFV4 (m.o.i. of 1.0 or 50). Each value is the mean of replicate samples from three parallel cultures. Error bars indicate sd. *P<0.05; **P<0.01 (Mann–Whitney test). The experiment was repeated twice (at each m.o.i.) with similar results.
