Species | S.# | Hemolytic activity | Antibacterial activity (inhibition zone mm) | Hem- aglutination | AChE inhibition | PP1 activation/inhibition | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B. subtilis | E. coli | aqueous | Organic | aqueous | organic | ||||||||||
aq | aqh | A | B | M | aq | aqh | A | B | M | ||||||
Hyrtios erecta | LI-10 | +A | 4A, 4B, 4M | iii | |||||||||||
Ircinia sp. | LI-39 | 2A, 2B, 2M | ++ | ||||||||||||
Ircinia sp. | 107 | ++A,B, +M | 9A,10B, 9M | + | + | + | i | ii | ii | i | |||||
Ircinia cf. Abseits | 132 | +A, ++B | 8A, 8B, 6M | + | + | + | a | i | ii | i | |||||
Pericharax heteroraphis | LI-35 | +++A, ++B, +M | 2A, 2B, 2M | a | i | ||||||||||
Phakellia stipitata | LI-5 | 4A, 3B, 4M | ii | ||||||||||||
Spongia sp. | LI-43 | +A | 2A, 2B, 2M | + | i | ||||||||||
Thorectandra sp. | LI-27 | +A, +B | 3A, 2B, 3M | +aq | + | +++ | ++ | +++ | i | i | |||||
Xestospongia pacifica | LI-47 | 3A, 3B, 3M | 2A, 1M | +++ | +++ | ++ | +++ | +++ | iii | i | iii | iii | iii |
aqueous unheated,
aqueous heated.
Organic extracts: A (acetone), B (butanol), M (methanol).
Hemolytic activity: +, moderate activity (t50 between 10 and 15 min); ++, strong activity (t50 between 5 and 10 min); +++, very strong activity (t50 between 0 and 5 min).
t50 = half-time of hemolysis, e.g. the time in which 50% of erythrocytes are lysed.
AChE inhibition: +, moderate inhibition (0–33%); ++, strong inhibition (34–66%); +++, very strong inhibition (67–100%).
PP1 activation/inhibition: a, activation (up to 100%); i, moderate inhibition (0–33%); ii, strong inhibition (34–66%); iii, very strong inhibition (67–100%).
S# sample number.