Table 4.
Modulation of protein phosphatase 1 (PP1) activity.
| Species | S# | Amount μg/mL | PP1 activation/inhibition | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| aqueous | organic | aqueous | organic | ||||||||
| unheated | heate | A | B | M | unheated | heated | A | B | M | ||
| d | |||||||||||
| Callyspongia plicifera | 9 | 58 | 48 | 23 | 44 | ||||||
| Ircinia felix | 59 | 283/78* | 273 | x2 | |||||||
| Ircinia felix | 93 | 244/70* | 200 | 176 | 275 | 790 | x1.5 | 33 | 67 | 100 | |
| Ircinia strobilina | 56 | 192/55* | 177 | x1.4 | |||||||
| Ircinia cf. abseits | 13 | 346/41* | 227 | x1.5 | |||||||
| 2 | |||||||||||
| Neofibularia nolitangere | 83 | 28 | 54 | 167 | 67 | 100 | 100 | ||||
| Spheciospongia | 69 | 78 | 50 | ||||||||
| vesparium | |||||||||||
| Verongula gigantea | 44 | 388/138* | 319 | x2 | |||||||
| Verongula rigida | 38 | 164/54* | 130 | x2 | |||||||
| Unidentified 1 | 21 | 73 | 117 | 673 | 100 | 100 | 100 | ||||
Organic extracts: A (acetone), B (butanol), M (methanol).
Activation is indicated in italics, and denotes a factor by which the PP1 activity is enhanced.
Inhibition is indicated in normal text, and denotes the % of inhibition.
*
protein.
S# sample number.