Table 1.
Demographic and clinical characteristics of children with ADHD separated according to their genotypes in the COMT Val108/158Met polymorphism.
| Met/Met (n=42) | Val/Met (n=115) | Val/Val (n=55) | Statistic and p-value | |
|---|---|---|---|---|
| M/F (% males) | 37/5 (88.1%) | 93/22 (80.9%) | 48/7 (87.3%) | χ2=1.8, df=2, p=0.41 |
| Age, yrs | 9.1 (2.0) | 9.0 (1.8) | 8.9 (1.7) | F2,209=0.1, p=0.9 |
| Household income (% < $20,000 per yr) | 40.5% | 41.9% | 41.8% | χ2=0.02, df=2, p=0.99 |
| Ethnic origin (Caucasian/other) | 38/4 | 104/11 | 46/9 | χ2=1.9, df=2, p=0.39 |
| WISQ-III full scale IQ | 97.2 (14.1) | 99.3 (14.5) | 97.8 (13.1) | F2,191=0.41, p=0.67 |
| Comorbidity (%) with: | ||||
| CD | 19.1% | 36.6% | 30.2% | χ2=4.4, df=2, p=0.11 |
| ODD | 38.1% | 40.4% | 39.6% | χ2=0.07, df=2, p=0.97 |
| AD | 38.5% | 43% | 57.5% | χ2=3.71, df=2, p=0.16 |
| MD | 15.8% | 12.9% | 8.3% | χ2=1.2, df=2, p=0.56 |
| CBCL total score | 68.3 (9) | 70.4 (9.3) | 69.7 (7.6) | F2,202=0.91, p=0.4 |