A previous suicide attempt
A psychiatric disorder, especially major depressive disorder, bipolar disorder, conduct disorder, and substance (alcohol and drug) use disorders
Psychiatric comorbidity, especially the combination of mood, disruptive, and substance abuse disorders
Personality disorders (especially cluster B disorders: antisocial, borderline, histrionic, narcissistic)
Impulsive aggression (the tendency to react to frustration or provocation with hostility or aggression)
Availability of lethal means
Feelings of hopelessness and worthlessness that often accompany depression
A family history of depression or suicide
Loss of a parent to death or divorce
Family discord
Physical and/or sexual abuse
Lack of a support network, poor relationships with parents or peers and feelings of social isolation
Dealing with homosexuality in an unsupportive family or community or hostile school environment