Table 3.
Performance on executive function measures in schizophrenia/schizophrenia spectrum disorder cases and matched controls in DIBS sample
| Cases N=26 | Controls N=24 | ||||||
|---|---|---|---|---|---|---|---|
| Wisconsin Card Sort Test (WCST) | Mean | SD | Mean | SD | pa | Parameter 95% CI | Generalized Linear Model Used |
| Total errors | 14.96 | 11.62 | 6.42 | 5.73 | <.001 | (.752, 1.189) | Binomial with 47 trials |
| Perseverative errors | 5.62 | 6.78 | 1.67 | 2.46 | <.001 | (.858, 1.608) | Binomial with 46 trials |
| Non-perseverative errors | 9.35 | 6.88 | 4.75 | 3.70 | <.001 | (.429, .934) | Binomial with 47 trials |
| Trail Making Test | |||||||
| Trails B time (sec.) | 104.39 | 50.79 | 52.92 | 12.36 | <.001 | (−.012, −.006) | Gamma |
| Trails A time (sec.) | 41.73 | 17.46 | 22.63 | 5.39 | <.001 | (−.028, −.015) | Gamma |
| Verbal Fluency Test | |||||||
| Letter fluency (total correct) | 12.23 | 3.67 | 14.46 | 2.96 | .073 | (−.311, .014) | Poisson |
| Category fluency (total correct) | 18.20 | 5.23 | 22.42 | 5.50 | .002 | (−.341, −.075) | Poisson |
| Ruff Figural Fluency Test (total correct) | 61.89 | 24.09 | 89.25 | 28.65 | <.001 | (−.412, −.274) | Poisson |
| WAIS Digit Span | |||||||
| Forward total | 9.23 | 2.66 | 10.54 | 1.98 | .173 | (−.518, .093) | Binomial with 16 trials |
| Backward total | 5.89 | 2.03 | 7.17 | 2.35 | .382 | (−.462, .177) | Binomial with 14 trials |
| Letter-Number Sequencing | 7.69 | 2.90 | 10.21 | 3.02 | .014 | (−.591, −.067) | Binomial with 21 trials |
| Auditory N-back | |||||||
| Two-back d-prime | 0.62 | 0.28 | 0.81 | 0.15 | .047 | (−.277, −.002) | Gaussian |
| Zero-back d-prime | 0.92 | 0.13 | 0.94 | 0.05 | .293 | (−.099, .030) | Gaussian |
a
Adjusted for WRAT III reading and based on appropriate Generalized Linear Model with canonical link.