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Rac1b-dependent cell motility and spreading require p120ctn. A, images of SCp2 cells transfected with YFP (vector) or YFP-Rac1b (Rac1b) and infected with nontarget shRNA or shRNA targeting p120ctn. Scale bar, 50 μm. B, scratch wound closure at 24 h, expressed as means ± S.E. (error bars) (p < 0.05) for nontarget/Rac1b versus p120 shRNA/Rac1b. C, area of cells at scratch border at 24 h, expressed as means ± S.E. (p < 0.05) for nontarget/Rac1b versus p120 shRNA/Rac1b.
