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. 2010 Apr 21;285(25):19267–19276. doi: 10.1074/jbc.M109.071860

FIGURE 3.

FIGURE 3.

Analysis by size-exclusion chromatography of PrP aggregation reaction time points. PrP alone (line) and PrP in presence of 0.4 mg/ml of C1q (dashed line) aggregations are analyzed by SEC over time. A, 1 h after aggregation. B, 4 h after aggregation. C, 6 h after aggregation. I′, oligomer I′; II, oligomer II; M, monomer. Incubation was performed at 40 °C. mAu, milliabsorbance units.