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. 2010 Apr 2;285(25):19561–19571. doi: 10.1074/jbc.M109.092916

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© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 3. — Effect of hypoxia on the PA metabolic status. A and B, NAD⁺, ADP, and ATP estimated in PA pre-contracted with KCl (30 mmol/liter; n = 5) and exposed to hypoxia for 5 min. Hypoxia increased NAD⁺ levels (A) and decreased ATP-to-ADP ratios (B), as compared with normoxia. C, NAD(P)H levels in homogenates of PA exposed to arsenic (10 μmol/liter; n = 5), rotenone (10 μmol/liter; n = 5), or antimycin (10 μmol/liter; n = 5). *, p < 0.05. D, effect of antimycin (10 μmol/liter; n = 5) on Glc-6-PD (G6PD) activity in PA.