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. Author manuscript; available in PMC: 2010 Nov 15.
Published in final edited form as: J Immunol. 2009 Oct 28;183(10):6545–6553. doi: 10.4049/jimmunol.0900867

Figure 4. Induction of Cxcl10, Ifit1, Irf7 and IFNb1 are more dependent on IRF3 following stimulation with short dsRNA molecules.

Figure 4

WT and IRF3-/- MEFs were treated with ν200 (A) or v3000 (B) for 6 hours. Quantitative RT-PCR was performed in triplicate with gene expression being normalized to the housekeeping gene (GAPDH) and expressed as fold change relative to mock treated cells. Results were analyzed using a one-way ANOVA with a tukey post test, ** p<0.01, *** p<0.001.