Table 1.

AR Kinetics Parameters. Parameters and baseline values for the AR kinetics model.

Parameter	Meaning	Value	Reference
	T:AR rate of association	.14 nM -1hr -1	[80]
	T:AR dissociation rate	.069 hr-1	[80]
	DHT:AR rate of association	.053 nM-1 hr -1	[80]
	DHT:AR dissociation rate	.018 hr -1	[80]
βR	Free AR degradation rate	ln(2)/3 hr -1	[82]
βT	Free T degradation rate	ln(2)/3 hr -1
βD	Free DHT degradation rate	ln(2)/9 hr -1	[61], see text
α	5α-reductase concentration	5.0 mg L -1	see text
kcat	Rate of T → DHT conversion by 5α-R	18 ± 15 nmol hr -1 mg -1	[97]
KM	Michaelis constant for 5α-R	75 ± 33 nM	[97]
KI	Michaelis constant for finasteride	.46 ± .21 nM	[97]