Table 2.
Growth Model Parameters. Parameters and baseline values for the prostate growth model.
| Parameter | Meaning | Value |
|---|---|---|
| θ1 | Half-maximal Ct for low androgen induced ROS | 30 nM |
| θ2 | Half-maximal Ct for high androgen induced ROS | 225 nM |
| μ | Background ROS level | .05 |
| n | Hill coefficient for low androgen induced ROS | 4 |
| m | Hill coefficient for high androgen induced ROS | 4 |
| φ1 | Half maximal Ct for high androgen induced proliferation | 110 nM |
| φ2 | Half maximal Ct for low androgen induced apoptosis | 40 nM |
| ϕ | Determines form of ROS induced proliferation signal | 4 |
| ω | Half-maximal S for ROS induced death | 1 |
| q | Hill coefficient for ROS induced death | 8 |
| σ | Mass action coefficient for proliferation attenuation | 1.5 × 10-10 cell-1 hour-1 |
| δ | Background death rate | .004 hour-1 |
| r | Maximum per capita growth rate | ln(2)/24 hour-1 |
| δ | Maximum per capita death rate | ln(2)/24 hour-1 |