Table 1.
Demographic and Clinical Characteristics of Study Subjects
| Characteristic | T2D Patients (917) | Controls (748) | P |
|---|---|---|---|
| Gender (M:F) | 422:495 | 373:375 | 0.126 |
| Mean Age (years) | 59.3 ± 10.9 | 58.7 ± 8.7 | 0.160 |
| Mean B.M.I. (kg/m2) | 27.7 ± 4.3 | 23.5 ± 2.2 | < 0.001 |
| Systolic BP (mmHg) | 140.7 ± 27.0 | 121.6 ± 14.4 | < 0.001 |
| Diastolic BP (mmHg) | 81.9 ± 12.6 | 77.9 ± 10.5 | < 0.001 |
| Hypertension2 | 420 (45.8) | 86 (18.0) | <0.001 |
| Fasting glucose (mmol/L) | 12.8 ± 5.3 | 5.1 ± 0.6 | < 0.001 |
| HbA1c (%) | 9.6 ± 3.9 | 4.5 ± 1.4 | < 0.001 |
| Age at disease onset (years) | 46.7 ± 10.9 | N/A | N/A |
| T2D Duration (years) | 12.6 ± 6.3 | N/A | N/A |
| Total cholesterol (mmol/L) | 5.3 ± 1.4 | 4.7 ± 1.2 | < 0.001 |
| Triglycerides (mmol/L) | 1.9 ± 1.3 | 1.2 ± 0.6 | < 0.001 |
| HDL (mmol/L) | 1.1 ± 0.3 | 1.2 ± 0.4 | < 0.001 |
| LDL (mmol/L) | 3.8 ± 1.4 | 2.8 ± 1.8 | < 0.001 |
| Urea (mmol/L) | 7.9 ± 4.8 | 5.6 ± 2.1 | < 0.001 |
1. Student t-test for continuous variables, chi square for categorical variables.
2. Defined as BP reading ≥ 145/90 mmHg, and/or use of anti-hypertension medication.