Table 5.
CAPN10 Haplotype Analysis
| Haplotype1 | Patients | Controls | P | Pc3 | OR (95% CI) |
|---|---|---|---|---|---|
| 1114 | 0.392 (719) 2 | 0.345 (516) 2 | 0.006 | 0.034 | 1.22 (1.06 - 1.41) |
| 112 | 0.072 (132) | 0.059 (88) | 0.147 | 0.615 | 1.24 (0.94 - 1.64) |
| 121 | 0.368 (675) | 0.399 (597) | 0.072 | 0.361 | 0.88 (0.76 - 1.01) |
| 122 | 0.080 (147) | 0.096 (144) | 0.115 | 0.520 | 0.82 (0.64 - 1.04) |
| 221 | 0.078 (143) | 0.086 (129) | 0.422 | 0.963 | 0.90 (0.70 - 1.15) |
| 222 | 0.010 (18) | 0.015 (22) | 0.259 | 0.834 | 0.66 (0.36 - 1.24) |
1. Haplotype frequency determined by the maximum likelihood method.
2. Haplotype frequency (number of haplotypes).
3. Pc = corrected P, calculated as per the Bonferroni method [Pc = 1 - (1 - P)n)], where n = number of comparisons.
4. CAPN10 haplotypes were coded as per the allele at each locus (wild-type = 1, mutant = 2); the first refers to UCSNP-43, the second to UCSNP-19, and the third to UCSNP-63.