Table 3.
Pairwise non-parametric Wilcoxon tests with Bonferroni adjustment to detect differences between classification groups and biomarker levels (comparisons to controls not shown)
| p53 | c-myc | imp1 | p62 | imp3 | cycA | cycB1 | cycD1 | cdk2 | survivin | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No Nodules | Solid Nodules | 1.000 | 0.031 | 1.000 | 0.001 | 1.000 | 1.000 | 0.228 | 0.351 | 1.000 | 0.022 |
| No Nodules | GGO | 0.750 | 0.810 | 0.128 | 1.000 | 0.680 | <0.001 | 1.000 | <0.001 | 1.000 | <0.001 |
| No Nodules | Cancer | 0.630 | 0.049 | 1.000 | 1.000 | 1.000 | 0.258 | 1.000 | 0.001 | 0.025 | 1.000 |
| Solid Nodules | GGO | 0.500 | <0.001 | <0.001 | 1.000 | 0.170 | 0.003 | 0.007 | <0.001 | 0.423 | <0.001 |
| Solid Nodules | Cancer | 0.630 | <0.001 | 0.009 | 1.000 | 1.000 | <0.001 | 1.000 | 0.018 | 0.001 | 0.139 |
| GGO | Cancer | 1.000 | 0.532 | 1.000 | 1.000 | 0.350 | <0.001 | 1.000 | <0.001 | 0.262 | <0.001 |