Table 1. Positive Control: Monensin.
Dose Range µg/ml | MAP | M. avium | M. tb. complex | |||||||
Human | Bovine | M. tb | BCG | |||||||
Dominic | UCF4 | Ben | ST-5 | 19698 | 303 | 25291 | 101 | 25177 | 19015 | |
Minimal | −27% | −92% | −95% | −76% | −56% | −30% | −12% | 7% | −76% | −29% |
Low | −48% | −92% | −98% | −95% | −78% | −72% | −21% | 13% | −98% | −66% |
Medium | −84% | −92% | −98% | −94% | −60% | −92% | −58% | −8% | −99% | −84% |
Maximal | −91% | −94% | −99% | −95% | −90% | −93% | −43% | −2% | −98% | −95% |
Our positive control antibiotic causes dose dependent inhibition in all but M. avium 101.
Shown are the effect of the test agent as either enhancement (%+ΔcGI) or inhibition of growth (- = %−ΔcGI) compared to control vials containing the same concentration of DMSO. See Methods for calculating %−ΔcGI. The dose ranges are “Minimal” = 0.25–2 µg/ml: “Low” = 4–8 µg/ml: “Medium” = 16–32 µg/ml and “Maximal” = 64–128 µg/ml. In these Tables “Maximal” is always the 128µg/ml data. For actual dose tested in individual experiments see the Abscissa on individual Figures.