Table 5. 5P-2Thiouracil.
Dose Range µg/ml | MAP | M. avium | M. tb. complex | |||||||
Human | Bovine | M. tb | BCG | |||||||
Dominic | UCF4 | Ben | ST-5 | 19698 | 303 | 25291 | 101 | 25177 | 19015 | |
Minimal | −6% | −16% | −11% | 27% | 44% | 55% | 20% | −5% | −20% | −2% |
Low | −8% | 6% | −45% | 40% | 32% | 25% | 4% | −6% | −34% | −41% |
Medium | −14% | −20% | −85% | 25% | −5% | −39% | −60% | −50% | −97% | −71% |
Maximal | −89% | −81% | −96% | −69% | −94% | −80% | −92% | −97% | −99% | −92% |
With this structural analog of 6-PTU there is dose dependent inhibition in eight of ten strains and inhibition at 128 µg/ml in the remaining two. Note that M. avium 101 is inhibited. See Legend to Table 1 for explanation.