Figure 6. Loss of presynaptic neurexin in embryo disrupts synaptic transmission.

A: Representative electrophysiological recordings of stimulus evoked synaptic currents (generated by electrical stimulation of presynaptic motor nerves), and spontaneous excitatory junction currents (sEJCs), from wild type embryonic NMJs and after disruption of neurexin expression. B: Quantification of EJC amplitude. C: Quantification of sEJC frequency. Numbers in parentheses represent the number of animals from which each measurement was made.