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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Biochim Biophys Acta. 2010 Feb 26;1806(1):66–73. doi: 10.1016/j.bbcan.2010.02.003

Fig. 2.

Fig. 2

PTK6 activation and downstream signaling. PTK6 is regulated by a variety of factors. Substrates (grey boxes) and interacting proteins may be localized to different cellular compartments (as indicated by double headed arrows). For example, β-catenin has well-established functions at the membrane and in the nucleus, and PTK6 influences β-catenin in both compartments. In most cases the effects that PTK6 has on substrates and binding partners in different cellular compartments merit further exploration. (OPN: osteopontin; HRG: heregulin).