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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2010 Mar 27;246(1-2):18–28. doi: 10.1016/j.taap.2010.03.013

Figure 1. TCDD alters the expression of differentiation markers on BMDCs.

Figure 1

Bone marrow cells were induced to differentiate into immature DCs with GM-CSF in the presence of vehicle (represented by dotted line in the histograms) or 10 nM TCDD (thick line as indicated in the histograms). Isotype staining is shown in gray lines. Non-adherent cells were harvested on day 7 and stained with CD11c as a DC lineage marker. MHC class II, CD86, CD54, CD11a and CD25 expression was determined on CD11c+ BMDCs by FACS analysis. Data shown represents non-adherent cells obtained from 4 separate flasks per treatment group and is representative of 3 independent experiments. *p<0.05 indicates significant differences between vehicle- and TCDD-treated groups.