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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: J Mol Cell Cardiol. 2010 Apr 1;49(2):322–329. doi: 10.1016/j.yjmcc.2010.03.017

Fig. 8.

Fig. 8

Scheme depicting the possible mechanism of action underlying ALDH2 knockout- induced exacerbation of ethanol exposure-induced change in Akt, GSK3β signaling molecules, mitochondrial function and ultimately development of alcoholic cardiomyopathy. The “T”-type arrow denotes inhibitory action.