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. Author manuscript; available in PMC: 2011 Jul 28.
Published in final edited form as: Neuroscience. 2010 Jan 28;168(4):1019–1035. doi: 10.1016/j.neuroscience.2010.01.037

Fig. 4.

Fig. 4

Fig. 4

A) The bottom line represents typical T2-MRI images of an uninjured spinal cord imaged in the same thoracic regions as those in the upper rows. Here we show 7 consecutive mages, around the SCI epicenter (images 1-3, right to left). The schematic representation above the uninjured cord shows the epicenter of SCI, and the approximate length of the cord that was imaged and presented here. The upper rows represent a moderately injured rat spinal cord imaged at 7 days, 2 wks, 4 wks and 8 wks after SCI. Numbers in white indicate individual images in columns, and red letters are time points after SCI (in rows). Arrows and asterisks are explained in the text. B) Increased water content was found not only at 3d after SCI (due to vasogenic edema) but also in the thoracic region of injured spinal cords 2 and 5months after SCI (∼20mm long; mean±S.D; p<0.05; reported in Nesic et al., 2006). C) MRI images of four SCI rats (1-4) 8 wks after SCI at the epicenter of SCI. Rat No. 4 had the largest cyst. D) Four T2 MRI images of an SCI rat whose cysts spanned ∼12 mm (about 4 segments) and enlarged from 4wks to 8 wks.