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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2010 Apr 25;246(1-2):8–17. doi: 10.1016/j.taap.2010.04.015

Figure 3.

Figure 3

A. Plasma alanine aminotransferase (ALT) activities as an indicator for APAP-induced hepatotoxicity were measured in C57BL/6 wild type and JNK2-deficient mice 6 h after 300 mg/kg APAP administration. Data represent means ± SE of n = 4 animals per group. *P<0.05 (compared to untreated controls). B. Representative liver sections of animals treated for 6 h with 300 mg/kg APAP were stained with H&E. (×50 for all panels).