Table 3.
Proteomics-determined differences in protein levels in PCAD IPL
| Protein | SwissProt Accession | Peptide Hits | p of id# | p of change% | Fold change | Regulation in PCAD | MW&/pl |
|---|---|---|---|---|---|---|---|
| Galectin-1 | P09832 | 13 | 1 e -11 | 0.019 | 0.22 | Down | 14/5.18 |
| Neurofilament medium subunit (NFM) | P07197 | 36 | 1 e -30 | 0.006 | 0.35 | Down | 102/4.75 |
| Aconitase (precursor) | Q99798 | 6 | 4 e -05 | 0.002 | 1.46 | Up | 85/7.32 |
| Fructose bisphosphate aldolase | P00441 | 6 | 3e -08 | 0.033 | 1.66 | Up | 48/7.98 |
| Cytochrome c oxidase (precursor) | P20674 | 4 | 4 e -09 | 0.033 | 0.23 | Down | 16/6.36 |
| Cathepsin D (precursor) | P07339 | 12 | 7 e -08 | 0.019 | 1.33 | Up | 45/6.10 |
| Cu, Zn SOD | P09772 | 3 | 1e -04 | 0.033 | 1.3 | Up | 16/5.68 |
| Peptidyl prolyl isomerase 1 (Pin1) | P62937 | 3 | 5 e -05 | 0.046 | 1.31 | Up | 18/7.82 |
| Septin 11 | Q9NVA2 | 4 | 3 e -09 | 0.047 | 1.64 | Up | 49/6.37 |
#
refers to probability associated with SEQUEST score
%
refers to p value of change in spot density between groups
&
approximate molecular weight, in kDa