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. 2010 Apr 14;4:19–26. doi: 10.2174/1875397301004010019

Fig. (3).

Fig. (3)

Interactions between TPH1 and Ring B of the inhibitors. The contact with one of the iron-coordinating water and the edge-to-face π-π interaction with Phe313 are common to the three complexes. LP-521834, left panel; LP-533401, middle panel; LP-534193, right panel.