Fig. (1).
Accumulation of ceramide in bronchial epithelial cells of Cftr-deficient mice. The figure demonstrates the accumulation of ceramide in bronchial epithelial cells of Cftr-deficient mice. Lungs from wildtype (wt) or Cftr-deficient mice (CftrMHH) were removed, fixed in 4% paraformaldehyde and stained with Cy3-coupled anti-ceramide antibodies. The sections were analysed by fluorescence microscopy. The fluorescence intensity represents the concentration of ceramide in epithelial cells. Printed with permission of Nature Medicine [11].