Fig. 1.
Characterization of sst4/vps27+ and sst6+ genes. (a) Domain structures of the Sch. pombe Sst4/Vps27 (SpSst4p) and Sac. cerevisiae Vps27 (ScVps27p) proteins. The shaded, hatched and closed boxes indicate the VHS, FYVE and UIM domains, respectively. (b) Domain structures of the Sch. pombe Sst6 (SpSst6p) and Sac. cerevisiae Vps23 (ScVps23p) proteins. ScVps23p possesses a UEV domain (hatched), similar to the catalytic domain of the E2 UBC enzyme, but SpSst6p has no domains defined by the SMART or Pfam databases.