Table 2.

Clinical modulation of angiogenesis[7]

Inhibition of angiogenesis	Stimulation of angiogenesis
Approved indications	Approved indications
Advanced cancer	Chronic wound - diabetic ulcer,
Ocular neovascularization	Experimental indications
Kaposi Sarcoma	Myocardial ischemia
Experimental indications	Peripheral ischemia
Hemangiomas	Cerebral ischemia
Psoriasis	Reconstructive surgery
Rheumatoid arthritis	Gastroduodenal ulcers
Endometriosis
Atherosclerosis

Adapted from Liekens et al. Angiogenesis: regulators and clinical applications[7]