Table 3.

Effect of Pluchea lanceolata (PL) on phagocytic function of murine macrophages

Treatment(Dose μg/ml)	% Phagocytosis (in vitro study) mean ± S.E.		Treatment (dose mg/kg)	Phagocytic Index (in vivo study) (Mean ± S.E.)
Naïve Control	25.23 ± 1.26	-	Sensitized Control	1.28 ± 0.12	-
Cyclosporine-A(10)	13.76 ± 0.33**	(45.46) ↓	Cyclosporine-A(5)	0.69 ± 0.10**	(46.09) ↓
PL (50)	24.12 ± 1.33	(4.39) ↓	PL (50)	1.24 ± 0.14	(3.12) ↓
PL (100)	22.48 ± 0.92	(10.89) ↓	PL (100)	1.20 ± 0.10	(6.25) ↓
PL (200)	21.79 ± 0.75*	(13.63) ↓	PL (200)	1.12 ± 0.12*	(12.50) ↓
PL (400)	19.80 ± 0.75**	(21.52) ↓	PL (400)	1.00 ± 0.10**	(21.87) ↓
PL (600)	17.35 ± 0.59**	(31.23) ↓	PL (600)	0.84 ± 0.12**	(44.53) ↓
PL (800)	18.26 ± 0.39**	(27.62) ↓	PL (800)	0.83 ± 0.14**	(45.31) ↓

^*P < 0.05;

^**P < 0.01 (Dunnett test, which compares test groups and the standard drug group with the control group); Figures in parentheses represent percent change in activity; number of animals per group = 6