Fig. 7.
Extensive dilation of the ER in 293T cells expressing FCV p39. TEM of 293T cells expressing the FCV p39 and HRPKDEL proteins obtained 24 h post-transfection. (a) and (b) 293T cells showing moderate dilation of the ER and nuclear envelope following expression of the FCV p39 protein. (c) and (d) 293T cells exhibiting extensive dilation of the ER following expression of the FCV p39 protein. In all panels, the ER-retained HRPKDEL is black due to electron density having being labelled with a heavy metal substrate. NE, Nuclear envelope. Bars, 1 μm (a), 2 μm (b, d), 5 μm (c).