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. Author manuscript; available in PMC: 2010 Jun 15.
Published in final edited form as: J Neurochem. 2009 Jan 22;108(6):1575–1584. doi: 10.1111/j.1471-4159.2009.05910.x

Fig. 1.

Fig. 1

Temporal characteristics of the effect of in vitro pre-incubation with DAT substrates on [3H]DA uptake into synaptosomes prepared from rat dSTR or NAc. After pre-incubation of synaptosomes with (A) 20 μM AMPH, (B) 10 μM DA, or (C) 10 μM METH for 5, 15, or 30 min and subsequent drug wash out, specific uptake of 0.5 nM [3H]DA was measured (see Methods for details). Mean value ± SEM shown for N = 4 per treatment and brain region. In both brain regions, two-way RMANOVA showed a main effect of drug treatment, but not a main effect of time or a treatment-time interaction.