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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Cell Mol Bioeng. 2010 Jun 1;3(2):139–150. doi: 10.1007/s12195-010-0121-3

Figure 1.

Figure 1

(A) Schematic representation of recombinant fragments of human nesprin-1α used in this work. Each black box indicates a spectrin-like repeat (SLR). The gray box indicates the adaptive domain (AD). Short grey box indicates the KASH domain. Our nesprin-1α polypeptide starts from residue 125 in Genbank accession no. AF444779. The SLRs were predicted by SMART, and the adaptive domain (AD) was named by virtue of its disorder predicted by DisEMBL but ordered structure measured in the full length protein. (B) SDS-PAGE analysis of purified recombinant SLR2-7, SLR2-5, SLR5-7 SLR2-7ΔAD and AD polypeptides.