Protein size measured by DLS for SLR2-7 and SLR2-7ΔAD as a function of increasing temperature. Protein size was measured at each indicated temperature, and average peak size was plotted; bars indicate standard deviation. Asterisks indicate that the plotted size is the average of two unresolved peaks, interpreted as a mixture of monomers and dimers at that temperature. With increasing temperature each construct changed from single-peak dimers, to presumed mixtures of dimers and monomers (asterisk), to single-peak monomers. SLR2-7ΔAD completely dissociates at near 42°C; SLR2-7 completely dissociates at near 58°C. Dissociated proteins then extended further, prior to denaturing above 54°C (SLR2-7ΔAD) or above 66°C (SLR2-7). (n=2 independent runs).