. 2010 May 18;49(24):4945–4956. doi: 10.1021/bi1004798

Table 1. Primarily Affected Tissues in Fe−S Cluster Synthesis Diseases^a.

	FXN	GLRX5	ISCU	ABCB7
erythroblasts		+		+
sensory and cerebellar neurons	+			+
cardiomyocytes	+		+
skeletal myocytes			+

The primarily affected cell types are sensory neurons and cardiac myocytes for frataxin-deficient Friedreich's ataxia, erythroblasts and cerebellar neurons for ABCB7-deficient XLSA/A, skeletal and cardiac myocytes for ISCU-deficient myopathy, and erythroblasts for GLRX5-deficient sideroblastic anemia.

Table 1. Primarily Affected Tissues in Fe−S Cluster Synthesis Diseasesa.

Table 1. Primarily Affected Tissues in Fe−S Cluster Synthesis Diseases^a.