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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Curr Opin Nephrol Hypertens. 2009 Nov;18(6):526–530. doi: 10.1097/MNH.0b013e328330d9d0

Table 2. Clinical Trials on Uric Acid and CKD.

1st Author Year Subjects Major Findings Ref.
Kanbay 2007 59 Hyperuricemic patients treated with allopurinol had increased GFR whereas patients with normal uric acid did not. (30)
Siu 2006 54 CKD patients with mean uric acid 9.75mg/dL treated with 100-300mg/d allopurinol, possible slower progression (31)