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. Author manuscript; available in PMC: 2010 Jun 15.
Published in final edited form as: Genes Chromosomes Cancer. 2009 May;48(5):419–428. doi: 10.1002/gcc.20651

Figure 1.

Figure 1

Copy number instability as measured by the proportion of each sample subject to DNA copy number gains in BRAF* tumors compared to NRAS* and BRAF/NRAS wt/wt (A) Total aberrations across the entire genome are higher in cell lines when compared to primary tumors (t-test; P = 0.0004), (B) Aberrations on chromosome 7 are more common in BRAF* tissues when compared to all BRAF wt tissues (P = 0.0199 and P = 0.0172 for tumors and cell lines respectively) (C) Specific gains of 7q32.1-36.3, represented in each sample as the green regions along the vertical ideogram of chromosome 7, strongly associate with BRAF* tissues.