TABLE 1.

Chromosomes Demonstrating Differential Aberration Rates in BRAF* or NRAS* Samples for Both Cell Lines and Tumors Include 4, 7 and 12.

			Tumors		Cell Lines
Chrom.	Mutation association	Aberration type	Mutant (n = 17)	Wild type (n = 26)	Mutant (n = 35)	Wild type (n = 17)	P-value (tumors;cell lines)
4	NRAS+	Loss	1.5 (3.9)	12.9 (22.8)	9.4 (28.3)	31.9 (37.1)	0.0120; 0.0359
12	NRAS+	Gain	0.8 (1.9)	7.1 (10.0)	0.5 (1.1)	6.0 (10.0)	0.0027; 0.0011
7	BRAF+	Gain	48.4 (35.3)	21.8 (34.2)	58.2 (37.9)	24.0 (38.0)	0.0199; 0.0172

Aberration rates were quantified by the proportion of the chromosome gained or lost. Standard deviations of these proportions appear in parentheses.