TABLE 2.

Subchromosomal Loci that Best Differentiate BRAF*, NRAS* and BRAF/NRAS^wt/wt Melanomas as Measured by Chi-Squared Analysis.

	Region	Association
BRAF* vs. WT	7q32.1-36.3	Gain, BRAF*
	5p15.31	Gain, BRAF*
	5p13.2	Gain, BRAF*
	8q21.11	Gain, WT
	8q24.11	Gain, WT
	11q24.2-24.3	Loss, BRAF*
	17q12-21.2	Loss, BRAF*
NRAS* vs. WT	4p16.1-15.2	Loss, WT
	5p15.31	Gain, WT; Loss NRAS*
	5p13.2	Gain, WT; Loss NRAS*
	7q31.11-36.3	Gain, WT
	17q.12	Loss, WT
	22p13	Loss, NRAS*
BRAF* vs. NRAS*	5p15.31	Gain, BRAF*
	7q32.1-35	Gain, BRAF*
	11q24.2-25	Loss, NRAS*
	16q21.1-qter	Loss BRAF*

Many regions differentiating BRAF* tumors from BRAF/NRAS^wt/wt also distinguish BRAF* from NRAS* tissues.