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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: J Cell Physiol. 2010 Jul;224(1):210–217. doi: 10.1002/jcp.22116

Fig. 5. β1/IGF-IR complex regulates prostate cancer cell proliferation in 3-D cultures through GLI1 expression.

Fig. 5

A model for the interaction between β1 integrins and IGF-IR regulating cell proliferation of prostate cancer cells in 3-D cultures in an AKT/GLI1-dependent manner is shown.