Figure 1.

Location of and linkage disequilibrium among TREK1 SNPs. The relative locations of TREK1 SNPs are presented on the right (graphic: chromosome 1, from top to bottom: 213.225–213.501 Mb). The LD plot (presented on the left) uses r ² as a measure of LD which ranges from 1 (or complete LD, indicated by black squares) to 0 (or absence of LD, indicated by white squares). In our sample, we observed high LD between rs2841608 and rs2841616 (r ² = 0.80) with low LD among all others (r ² ≤ 0.14). Plotted using Haploview [Barrett et al.,2005].