Table 1.
Body and uterus weight and plasma 17β-estradiol and cholesterol levels in C57 and ApoE-deficient mice groups
| Parameters | C57 | ApoE | ||
|---|---|---|---|---|
| Sham | OVX | Sham | OVX | |
| Body weight (g) | 25.9 ± 0.5 (22) | 26.8 ± 0.6 (22) | 26.3 ± 0.6 (12) | 25.5 ± 0.7 (12) |
| Uterus weight (mg) | 30.3 ± 1.8 (22) | 5.4 ± 0.7* (22) | 36.2 ± 1.6 (12) | 5.9 ± 1.3† (12) |
| Uterus weight/body weight (mg/g) | 1.18 ± 0.10 (22) | 0.20 ± 0.02* (22) | 1.38 ± 0.07 (12) | 0.23 ± 0.05† (12) |
| Plasma 17β-estradiol (pmol/L) | 128 ± 8 (14) | 61 ± 4* (13) | 152 ± 12 (11) | 71 ± 3† (9) |
| Plasma cholesterol (mmol/L) | 1.66 ± 0.13 (16) | 1.42 ± 0.11 (13) | 10.77 ± 1.02* (11) | 9.64 ± 0.88* (9) |
Data are reported as means ± SEM of the number of animals indicated in parentheses.
OVX: ovariectomized. *P < 0.05 vs C57 Sham; †P < 0.05 vs ApoE Sham (ANOVA).