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. 2010 Jun 15;4(6):e710. doi: 10.1371/journal.pntd.0000710

Figure 2. Supervised comparisons between expression values of pre-defined patient categories.

Figure 2

(A) Venn diagram identifying genes (n = 310) that are up-regulated in common between all categories of DENV-infected patients relative to convalescent samples. Up-regulated genes were identified through two-way SAM comparisons between each group (DF, n = 20; DHF, n = 6; DSS, n = 8) and convalescent samples (n = 6). GO analysis was used to identify “biological processes” significantly over-represented in this list of “common” genes from all DENV-infected patients. (B) Multiple two-way SAM comparisons between patients of different clinical categories showing the numbers of significantly up or down-regulated genes in each comparison at a false discovery rate of 5%. Genes identified through these two-way comparisons are listed in Table S5.