Table 4.
Multivariate analysis on OS and DFS in 143 colorectal cancer patients
| DFS | OS | |||||
|---|---|---|---|---|---|---|
| HR | 95% C.I | p | HR | 95% C.I | p | |
| VEGF, <825 vs. ≥825 pg/mL* | 1.281 | 0.41-4.03 | 0.672 | 4.779 | 1.15-19.94 | 0.032 |
| IL-6, <11.68 vs. ≥11.68 pg/mL* | 1.284 | 0.44-3.73 | 0.646 | 1.391 | 0.36-5.44 | 0.634 |
| CRP, <0.18 vs. ≥0.18 mg/dL* | 1.030 | 0.38-2.80 | 0.954 | 0.869 | 0.22-3.51 | 0.844 |
| CEA, <5 vs. ≥5 ng/mL | 8.391 | 2.51-28.07 | 0.001 | 7.981 | 1.44-44.10 | 0.012 |
| Tumor size, <5 vs. ≥5 cm | 0.210 | 0.06-0.81 | 0.023 | 3.448 | 0.29-41.06 | 0.327 |
| T, T1 vs. T2 vs. T3 vs. T4 | 2.479 | 0.94-6.57 | 0.068 | 5.963 | 0.76-46.87 | 0.090 |
| N, N0 vs. N1 vs. N2 | 4.807 | 2.38-9.72 | <0.001 | 5.867 | 2.86-86.20 | 0.002 |
| Stage, I vs. II vs. III | 0.783 | 0.12-5.10 | 0.798 | 0.042 | 0.00-0.67 | 0.025 |
| Age, <60 vs. ≥60 | 0.726 | 0.20-2.59 | 0.622 | 11.91 | 2.14-66.33 | 0.005 |
* cutoff value by ROC curve