. 2009 Dec 18;66(3):547–558. doi: 10.1007/s00280-009-1195-2

Table 2.

Cell cycle modulation after 24 h drug exposure

Cell line	Treatment	G1^a phase (%)	∆G1^b	S-phase (%)	∆S	G2/M phase (%)	∆G2/M
HT 29	Control	69.3		26.2		4.5
	L-OHP	48.9	−20.4^*	40.9	+14.7^*	10.2	+5.7^*
	MTA	75.5	+6.2	24.5	−1.7	0	−4.5^*
WiDr	Control	69.7		24.5		5.8
	L-OHP	61.9	−7.8	27.5	+3.0	10.5	+4.7
	MTA	72.2	+2.5	27.8	+3.3	0	−5.8^*
SW620	Control	49.5		44.9		5.5
	L-OHP	37.5	−12.0^*	57.1	+12.2^*	5.4	−0.1
	MTA	67.2	+17.7^*	30.2	−14.7^*	2.6	−2.9
LS174T	Control	56.4		33.5		10.1
	L-OHP	41.1	−15.3^*	50.0	+16.5^*	8.9	−1.2
	MTA	65.1	+8.7	34.6	+1.1	0.4	−9.7^*

^aMean data from three independent experiments (SD < 10% in all cases)

^bDifferences (Δ) calculated with respect to controls

* P < 0.05