Table 3.
Comparison of CDAD in Medical vs. Post-Surgical Patients
Medical CDAD (n = 432) | Post-Surgical CDAD (n = 49) | p value | |
---|---|---|---|
Age | 67.9 ± 17.1 | 64.4 ± 15.8 | 0.09 |
Male | 162 (37.5) | 12 (24.5) | 0.07 |
Race/Ethnicity | 0.89 | ||
White | 121 (28.0) | 14 (28.6) | 0.93 |
Black | 142 (32.9) | 15 (30.6) | 0.75 |
Hispanic | 142 (32.9) | 18 (36.7) | 0.59 |
Other/Unknown | 27 (6.2) | 2 (4.1) | 0.55 |
Any antibiotic given* | 368 (85.2) | 48 (98.0) | 0.01 |
Cephalosporin† | 131 (30.3) | 9 (18.4) | 0.08 |
Quinolone | 196 (45.4) | 21 (42.9) | 0.74 |
Clindamycin | 10 (2.3) | 3 (6.1) | 0.12 |
Imipenim | 29 (6.7) | 5 (10.2) | 0.37 |
Proton-Pump Inhibitor given‡ | 252 (58.3) | 19 (38.8) | 0.009 |
Prior Hospitalization§ | 290 (67.1) | 21 (42.9) | 0.001 |
Admission Albumin | 2.72 ± 0.71 | 2.66 ± 0.70 | 0.69 |
White Blood Cell Count∥ | 15.7 ± 14.2 | 14.5 ± 5.4 | 0.49 |
Charlson Score | 3.13 ± 2.48 | 3.63 ± 3.25 | 0.54 |
Community Aquired¶ | 162 (37.5) | 3 (6.1) | < 0.001 |
Hospital | 0.47 | ||
Moses Division Hospital | 268 (62.0) | 33 (67.3) | |
Weiler Division Hospital | 164 (38.0) | 16 (32.7) |
Continuous variables reported as mean ± standard deviation and compared using a t-test or Wilcoxon rank-sum test as appropriate
Dichotomous variables reported as number (percent) and compared using a chi-squared test
any antibacterial given within 30 days before diagnosis of CDAD
3rd or 4th generation cephalosporins: cefipime, ceftriaxone, cefpodoxime, cefotaxime
any PPI given within 10 days before diagnosis of CDAD
any previous hospitalization within 180 days before diagnosis of CDAD
measured at the time of CDAD diagnosis
infection discovered within 48hrs of admission