Table 1.
Serum proteins that are differentially expressed between ovarian cancer patients and normal controls
| IPI number | Normalized ASAP ratios (normal/cancer) | Ratio SD | Number of unique peptides | Total number of peptides | Description |
|---|---|---|---|---|---|
| Over expressed in cancer | |||||
| IPI00791343 | 0.00 | 0 | 2 | 2 | 261 kDa protein |
| IPI00102300 | 0.00 | 0 | 3 | 3 | Isoform 3 of platelet glycoprotein VI |
| IPI00783169 | 0.06 | 0.01 | 74 | 160 | Coagulation factor XII |
| IPI00747585 | 0.06 | 0.02 | 2 | 3 | Transketolase-like 1 |
| IPI00384040 | 0.14 | 0.17 | 2 | 5 | 58 kDa protein |
| IPI00022417 | 0.14 | 0.02 | 2 | 4 | LRG1 |
| IPI00478493 | 0.19 | 0.12 | 10 | 13 | HP protein |
| IPI00374218 | 0.23 | 0.48 | 3 | 3 | Hypothetical protein |
| IPI00303210 | 0.24 | 0.03 | 4 | 5 | Isoform 2 of ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| IPI00216641 | 0.28 | 0.31 | 3 | 3 | Isoform 2 of contactin-1 |
| IPI00642425 | 0.29 | 0.04 | 5 | 6 | Cell surface glycoprotein |
| IPI00167093 | 0.29 | 0.26 | 7 | 8 | Complement factor H-related 1 |
| IPI00027509 | 0.29 | 0.1 | 4 | 6 | MMP-9 |
| IPI00029235 | 0.31 | 0.36 | 7 | 10 | IGFBP 6 |
| IPI00026482 | 0.32 | 0.17 | 2 | 2 | 10 kDa protein |
| IPI00639937 | 0.33 | 0.17 | 55 | 91 | B-factor |
| IPI00430820 | 0.34 | 0.66 | 8 | 12 | IGKV1-5 protein |
| IPI00018274 | 0.37 | 0.3 | 2 | 2 | Isoform 1 of epidermal growth factor receptor |
| IPI00022371 | 0.38 | 0.16 | 10 | 12 | Histidine-rich glycoprotein |
| IPI00642991 | 0.42 | 0.39 | 11 | 16 | Fibronectin 1 isoform 6 |
| IPI00020557 | 0.46 | 0.17 | 4 | 4 | Low-density lipoprotein receptor-related protein 1 |
| IPI00216694 | 0.49 | 0.18 | 3 | 5 | Plastin 3 |
| IPI00006114 | 0.50 | 0.16 | 10 | 16 | Pigment epithelium-derived factor |
| IPI00022488 | 0.51 | 0.25 | 150 | 453 | Hemopexin |
| IPI00784458 | 0.52 | 0.39 | 5 | 5 | 312 kDa protein |
| IPI00030385 | 0.53 | 0.08 | 2 | 2 | CDNA FLJ13813 fis |
| IPI00021727 | 0.53 | 0.13 | 23 | 33 | C4b-binding protein alpha chain |
| IPI00018305 | 0.53 | 0.73 | 10 | 24 | IGFBP 3 |
| IPI00298971 | 0.54 | 0.19 | 18 | 36 | Vitronectin |
| IPI00294004 | 0.54 | 0.17 | 6 | 6 | Vitamin K-dependent protein S |
| IPI00790993 | 0.56 | 0.19 | 12 | 15 | 104 kDa protein |
| IPI00555752 | 0.56 | 0.06 | 6 | 7 | Complement component 4 binding protein |
| IPI00297284 | 0.56 | 0.28 | 26 | 48 | IGFBP 2 |
| IPI00032220 | 0.56 | 0.25 | 15 | 24 | Angiotensinogen |
| IPI00550991 | 0.57 | 0.14 | 22 | 40 | Isoform 1 of Alpha-1-antichymotrypsin |
| IPI00022395 | 0.57 | 0.25 | 80 | 149 | Complement component C9 |
| IPI00554498 | 0.58 | 0.11 | 3 | 4 | l-lactate dehydrogenase C chain |
| IPI00743064 | 0.59 | 0.04 | 4 | 4 | 23 kDa protein |
| IPI00290571 | 0.59 | 0.33 | 2 | 2 | F-box only protein 30 |
| IPI00027780 | 0.60 | 0.42 | 6 | 7 | 72 kDa type IV collagenase |
| IPI00292530 | 0.61 | 0.17 | 11 | 13 | Inter-alpha-trypsin inhibitor heavy chain H1 |
| IPI00022331 | 0.62 | 0.06 | 3 | 3 | Phosphatidylcholine-sterol acyltransferase |
| Under expressed in cancer | |||||
| IPI00647344 | 2.58 | 0.33 | 2 | 2 | Similar to cytosolic non-specific dipeptidase |
| IPI00022434 | 2.87 | 0.41 | 7 | 9 | ALB protein |
| IPI00411302 | 3.27 | 0.81 | 2 | 2 | Transmembrane protease |
| IPI00004957 | 3.44 | 2.17 | 2 | 2 | ANGPTL3 |
| IPI00645500 | 3.60 | 0.41 | 2 | 2 | Complement component 2 |
| IPI00022432 | 6.26 | 1.03 | 15 | 29 | Transthyretin |
| IPI00514342 | 918.59 | 17.6 | 2 | 2 | Selectin E |
| IPI00025426 | 918.59 | 17.6 | 11 | 81 | Pregnancy zone protein |