Table IV.
Mitochondrial Translation Factors.
Name | Official symbol |
Function(s) in Translation | Associated Disease Relation |
---|---|---|---|
IF2mt | MTIF2 | Initiation | Parkinson's Disease |
IF3mt | MTIF3 | Initiation Subunit disassociation |
|
EF-Tumt | TUFM | Delivers aminoacylated tRNAs Translation fidelity Protein folding chaperone |
Infantile encephalopathy |
EF-Tsmt | TSFM | Guanine nucleotide exchange factor for EF- Tumt |
Encephalomyopathy Hypertrophic cardiomyopathy |
EF-G1mt | GFM1 | Translocation | Infantile encephalopathy Early-onset Leigh syndrome Progressive hepatoencephalopathy |
EF-G2mt | GFM2 | Ribosome recycling | |
mtRRF | MRRF | Ribosome disassembly | |
mtRF1 | MTRF1 | Translation termination? | |
mtRF1a | MTRF1L | Translation termination |